COURSE OVERVIEW

This practical and highly-interactive course includes various practical sessions and exercises. Theory learnt will be applied using our state-of-the-art simulators. 

 

This course is designed to provide participants with a detailed and up-to-date overview of PEG (Polyethylene Gloycol) Manufacturing & Process Troubleshooting. It covers the applications of PEG in pharmaceuticals, cosmetics and industrial uses; the ethylene oxide (EO) and ethylene glycol (EG) chemistry catalysts use in PEG synthesis, reaction mechanisms and by-products and side reactions; the difference between batch versus continuous PEG production; the reactor types and configurations, process flow diagrams (PFDs) for PEG synthesis and key process parameters affecting PEG quality; and the equipment used in PEG manufacturing, safety considerations in PEG manufacturing and quality control and analytical techniques. 

Further, the course will also discuss the ethoxylation reaction mechanism, catalyst selection and optimization, reaction conditions and process control; the automation and instrumentation purification, separation techniques and yield optimization strategies; the common production issues in PEG manufacturing, troubleshooting ethoxylation reactions and the temperature and pressure-related issues; the equipment malfunctions and preventive maintenance; and the quality control failures, troubleshooting, waste management and environmental compliance. 

During this interactive course, participants will learn the process optimization techniques and scale-up challenges in PEG manufacturing; the advanced catalysis for improved efficiency, energy efficiency and sustainability; the role of loT in process monitoring, predictive maintenance using Al, smart sensors for inline quality control and digital twins for PEG process simulation; the hazard identification in PEG plants, HAZOP and FMEA studies, fire and explosion risk mitigation and emergency shutdown procedures; the FDA, EU and REACH guidelines for PEG; the good manufacturing practices (GMP) for pharmaceutical PEG; and the environmental workplace safety regulations.